Tech
So you’ve heard these AI terms and nodded along; let’s fix that
Artificial intelligence is changing the world, and simultaneously inventing a whole new language to describe how it’s doing it. Spend five minutes reading about AI and you’ll run into LLMs, RAG, RLHF, and a dozen other terms that can make even very smart people in the tech world feel insecure. This glossary is our attempt to fix that. We update it regularly as the field evolves, so consider it a living document, much like the AI systems it describes.
Artificial general intelligence, or AGI, is a nebulous term. But it generally refers to AI that’s more capable than the average human at many, if not most, tasks. OpenAI CEO Sam Altman once described AGI as the “equivalent of a median human that you could hire as a co-worker.” Meanwhile, OpenAI’s charter defines AGI as “highly autonomous systems that outperform humans at most economically valuable work.” Google DeepMind’s understanding differs slightly from these two definitions; the lab views AGI as “AI that’s at least as capable as humans at most cognitive tasks.” Confused? Not to worry — so are experts at the forefront of AI research.
An AI agent refers to a tool that uses AI technologies to perform a series of tasks on your behalf — beyond what a more basic AI chatbot could do — such as filing expenses, booking tickets or a table at a restaurant, or even writing and maintaining code. However, as we’ve explained before, there are lots of moving pieces in this emergent space, so “AI agent” might mean different things to different people. Infrastructure is also still being built out to deliver on its envisaged capabilities. But the basic concept implies an autonomous system that may draw on multiple AI systems to carry out multistep tasks.
Think of API endpoints as “buttons” on the back of a piece of software that other programs can press to make it do things. Developers use these interfaces to build integrations — for example, allowing one application to pull data from another, or enabling an AI agent to control third-party services directly without a human manually operating each interface. Most smart home devices and connected platforms have these hidden buttons available, even if ordinary users never see or interact with them. As AI agents grow more capable, they are increasingly able to find and use these endpoints on their own, opening up powerful — and sometimes unexpected — possibilities for automation.
Given a simple question, a human brain can answer without even thinking too much about it — things like “which animal is taller, a giraffe or a cat?” But in many cases, you often need a pen and paper to come up with the right answer because there are intermediary steps. For instance, if a farmer has chickens and cows, and together they have 40 heads and 120 legs, you might need to write down a simple equation to come up with the answer (20 chickens and 20 cows).
In an AI context, chain-of-thought reasoning for large language models means breaking down a problem into smaller, intermediate steps to improve the quality of the end result. It usually takes longer to get an answer, but the answer is more likely to be correct, especially in a logic or coding context. Reasoning models are developed from traditional large language models and optimized for chain-of-thought thinking thanks to reinforcement learning.
(See: Large language model)
This is a more specific concept that an “AI agent,” which means a program that can take actions on its own, step by step, to complete a goal. A coding agent is a specialized version applied to software development. Rather than simply suggesting code for a human to review and paste in, a coding agent can write, test, and debug code autonomously, handling the kind of iterative, trial-and-error work that typically consumes a developer’s day. These agents can operate across entire codebases, spotting bugs, running tests, and pushing fixes with minimal human oversight. Think of it like hiring a very fast intern who never sleeps and never loses focus — though, as with any intern, a human still needs to review the work.
Although somewhat of a multivalent term, compute generally refers to the vital computational power that allows AI models to operate. This type of processing fuels the AI industry, giving it the ability to train and deploy its powerful models. The term is often a shorthand for the kinds of hardware that provides the computational power — things like GPUs, CPUs, TPUs, and other forms of infrastructure that form the bedrock of the modern AI industry.
A subset of self-improving machine learning in which AI algorithms are designed with a multi-layered, artificial neural network (ANN) structure. This allows them to make more complex correlations compared to simpler machine learning-based systems, such as linear models or decision trees. The structure of deep learning algorithms draws inspiration from the interconnected pathways of neurons in the human brain.
Deep learning AI models are able to identify important characteristics in data themselves, rather than requiring human engineers to define these features. The structure also supports algorithms that can learn from errors and, through a process of repetition and adjustment, improve their own outputs. However, deep learning systems require a lot of data points to yield good results (millions or more). They also typically take longer to train compared to simpler machine learning algorithms — so development costs tend to be higher.
(See: Neural network)
Diffusion is the tech at the heart of many art-, music-, and text-generating AI models. Inspired by physics, diffusion systems slowly “destroy” the structure of data — for example, photos, songs, and so on — by adding noise until there’s nothing left. In physics, diffusion is spontaneous and irreversible — sugar diffused in coffee can’t be restored to cube form. But diffusion systems in AI aim to learn a sort of “reverse diffusion” process to restore the destroyed data, gaining the ability to recover the data from noise.
Distillation is a technique used to extract knowledge from a large AI model with a ‘teacher-student’ model. Developers send requests to a teacher model and record the outputs. Answers are sometimes compared with a dataset to see how accurate they are. These outputs are then used to train the student model, which is trained to approximate the teacher’s behavior.
Distillation can be used to create a smaller, more efficient model based on a larger model with a minimal distillation loss. This is likely how OpenAI developed GPT-4 Turbo, a faster version of GPT-4.
While all AI companies use distillation internally, it may have also been used by some AI companies to catch up with frontier models. Distillation from a competitor usually violates the terms of service of AI API and chat assistants.
This refers to the further training of an AI model to optimize performance for a more specific task or area than was previously a focal point of its training — typically by feeding in new, specialized (i.e., task-oriented) data.
Many AI startups are taking large language models as a starting point to build a commercial product but are vying to amp up utility for a target sector or task by supplementing earlier training cycles with fine-tuning based on their own domain-specific knowledge and expertise.
(See: Large language model [LLM])
A GAN, or Generative Adversarial Network, is a type of machine learning framework that underpins some important developments in generative AI when it comes to producing realistic data — including (but not only) deepfake tools. GANs involve the use of a pair of neural networks, one of which draws on its training data to generate an output that is passed to the other model to evaluate.
The two models are essentially programmed to try to outdo each other. The generator is trying to get its output past the discriminator, while the discriminator is working to spot artificially generated data. This structured contest can optimize AI outputs to be more realistic without the need for additional human intervention. Though GANs work best for narrower applications (such as producing realistic photos or videos), rather than general purpose AI.
Hallucination is the AI industry’s preferred term for AI models making stuff up – literally generating information that is incorrect. Obviously, it’s a huge problem for AI quality.
Hallucinations produce GenAI outputs that can be misleading and could even lead to real-life risks — with potentially dangerous consequences (think of a health query that returns harmful medical advice).
The problem of AIs fabricating information is thought to arise as a consequence of gaps in training data. Hallucinations are contributing to a push toward increasingly specialized and/or vertical AI models — i.e. domain-specific AIs that require narrower expertise – as a way to reduce the likelihood of knowledge gaps and shrink disinformation risks.
Inference is the process of running an AI model. It’s setting a model loose to make predictions or draw conclusions from previously seen data. To be clear, inference can’t happen without training; a model must learn patterns in a set of data before it can effectively extrapolate from this training data.
Many types of hardware can perform inference, ranging from smartphone processors to beefy GPUs to custom-designed AI accelerators. But not all of them can run models equally well. Very large models would take ages to make predictions on, say, a laptop versus a cloud server with high-end AI chips.
[See: Training]
Large language models, or LLMs, are the AI models used by popular AI assistants, such as ChatGPT, Claude, Google’s Gemini, Meta’s AI Llama, Microsoft Copilot, or Mistral’s Le Chat. When you chat with an AI assistant, you interact with a large language model that processes your request directly or with the help of different available tools, such as web browsing or code interpreters.
LLMs are deep neural networks made of billions of numerical parameters (or weights, see below) that learn the relationships between words and phrases and create a representation of language, a sort of multidimensional map of words.
These models are created from encoding the patterns they find in billions of books, articles, and transcripts. When you prompt an LLM, the model generates the most likely pattern that fits the prompt.
(See: Neural network)
Memory cache refers to an important process that boosts inference (which is the process by which AI works to generate a response to a user’s query). In essence, caching is an optimization technique, designed to make inference more efficient. AI is obviously driven by high-octane mathematical calculations and every time those calculations are made, they use up more power. Caching is designed to cut down on the number of calculations a model might have to run by saving particular calculations for future user queries and operations. There are different kinds of memory caching, although one of the more well-known is KV (or key value) caching. KV caching works in transformer-based models, and increases efficiency, driving faster results by reducing the amount of time (and algorithmic labor) it takes to generate answers to user questions.
(See: Inference)
A neural network refers to the multi-layered algorithmic structure that underpins deep learning — and, more broadly, the whole boom in generative AI tools following the emergence of large language models.
Although the idea of taking inspiration from the densely interconnected pathways of the human brain as a design structure for data processing algorithms dates all the way back to the 1940s, it was the much more recent rise of graphical processing hardware (GPUs) — via the video game industry — that really unlocked the power of this theory. These chips proved well suited to training algorithms with many more layers than was possible in earlier epochs — enabling neural network-based AI systems to achieve far better performance across many domains, including voice recognition, autonomous navigation, and drug discovery.
(See: Large language model [LLM])
Open source refers to software — or, increasingly, AI models — where the underlying code is made publicly available for anyone to use, inspect, or modify. In the AI world, Meta’s Llama family of models is a prominent example; Linux is the famous historical parallel in operating systems. Open source approaches allow researchers, developers, and companies around the world to build on top of one another’s work, accelerating progress and enabling independent safety audits that closed systems cannot easily provide. Closed source means the code is private — you can use the product but not see how it works, as is the case with OpenAI’s GPT models — a distinction that has become one of the defining debates in the AI industry.
Parallelization means doing many things at the same time instead of one after another — like having 10 employees working on different parts of a project at the same time instead of one employee doing everything sequentially. In AI, parallelization is fundamental to both training and inference: modern GPUs are specifically designed to perform thousands of calculations in parallel, which is a big reason why they became the hardware backbone of the industry. As AI systems grow more complex and models grow larger, the ability to parallelize work across many chips and many machines has become one of the most important factors in determining how quickly and cost-effectively models can be built and deployed. Research into better parallelization strategies is now a field of study in its own right.
RAMageddon is the fun new term for a not-so-fun trend that is sweeping the tech industry: an ever-increasing shortage of random access memory, or RAM chips, which power pretty much all the tech products we use in our daily lives. As the AI industry has blossomed, the biggest tech companies and AI labs — all vying to have the most powerful and efficient AI — are buying so much RAM to power their data centers that there’s not much left for the rest of us. And that supply bottleneck means that what’s left is getting more and more expensive.
That includes industries like gaming (where major companies have had to raise prices on consoles because it’s harder to find memory chips for their devices), consumer electronics (where memory shortage could cause the biggest dip in smartphone shipments in more than a decade), and general enterprise computing (because those companies can’t get enough RAM for their own data centers). The surge in prices is only expected to stop after the dreaded shortage ends but, unfortunately, there’s not really much of a sign that’s going to happen anytime soon.
Like AGI, recursive self-improvement is a threshhold for how smart AI can get, and how little it may rely on humans. In the RSI scenario, AI models start improving themselves without human intervention, leading to a huge acceleration in capabilities and autonomy. In some tellings, this would be a cataclysmic moment akin to the singularity, a moment when AI models become immune to outside intervention. But RSI also describes a basic capability — can an AI model design its own successor? — which makes it much easier for engineers to try to build it. A number of recent AI startups have set out to build recursively self-improving models, but most of them dismiss the apocalyptic implications, presenting RSI as simply the next frontier for research.
Reinforcement learning is a way of training AI where a system learns by trying things and receiving rewards for correct answers — like training your beloved pet with treats, except the “pet” in this scenario is a neural network and the “treat” is a mathematical signal indicating success. Unlike supervised learning, where a model is trained on a fixed dataset of labeled examples, reinforcement learning lets a model explore its environment, take actions, and continuously update its behavior based on the feedback it receives. This approach has proven especially powerful for training AI to play games, control robots, and, more recently, sharpen the reasoning ability of large language models. Techniques like reinforcement learning from human feedback, or RLHF, are now central to how leading AI labs fine-tune their models to be more helpful, accurate, and safe.
When it comes to human-machine communication, there are some obvious challenges — people communicate using human language, while AI programs execute tasks through complex algorithmic processes informed by data. Tokens bridge that gap: they are the basic building blocks of human-AI communication, representing discrete segments of data that have been processed or produced by an LLM. They are created through a process called tokenization, which breaks down raw text into bite-sized units a language model can digest, similar to how a compiler translates human language into binary code a computer can understand. In enterprise settings, tokens also determine cost — most AI companies charge for LLM usage on a per-token basis, meaning the more a business uses, the more it pays.
So again, tokens are the small chunks of text — often parts of words rather than whole ones — that AI language models break language into before processing it; they are roughly analogous to “words” for the purposes of understanding AI workloads. Throughput refers to how much can be processed in a given period of time, so token throughput is essentially a measure of how much AI work a system can handle at once. High token throughput is a key goal for AI infrastructure teams, since it determines how many users a model can serve simultaneously and how quickly each of them receives a response. AI researcher Andrej Karpathy has described feeling anxious when his AI subscriptions sit idle — echoing the feeling he had as a grad student when expensive computer hardware wasn’t being fully utilized — a sentiment that captures why maximizing token throughput has become something of an obsession in the field.
Developing machine learning AIs involves a process known as training. In simple terms, this refers to data being fed in in order that the model can learn from patterns and generate useful outputs. Essentially, it’s the process of the system responding to characteristics in the data that enables it to adapt outputs towards a sought-for goal — whether that’s identifying images of cats or producing a haiku on demand.
Training can be expensive because it requires lots of inputs, and the volumes required have been trending upwards — which is why hybrid approaches, such as fine-tuning a rules-based AI with targeted data, can help manage costs without starting entirely from scratch.
[See: Inference]
A technique where a previously trained AI model is used as the starting point for developing a new model for a different but typically related task – allowing knowledge gained in previous training cycles to be reapplied.
Transfer learning can drive efficiency savings by shortcutting model development. It can also be useful when data for the task that the model is being developed for is somewhat limited. But it’s important to note that the approach has limitations. Models that rely on transfer learning to gain generalized capabilities will likely require training on additional data in order to perform well in their domain of focus
(See: Fine tuning)
Validation loss is a number that tells you how well an AI model is learning during training — and lower is better. Researchers track it closely as a kind of real-time report card, using it to decide when to stop training, when to adjust hyperparameters, or whether to investigate a potential problem. One of the key concerns it helps flag is overfitting, a condition in which a model memorizes its training data rather than truly learning patterns it can generalize to new situations. Think of it as the difference between a student who genuinely understands the material and one who simply memorized last year’s exam — validation loss helps reveal which one your model is becoming.
Weights are core to AI training, as they determine how much importance (or weight) is given to different features (or input variables) in the data used for training the system — thereby shaping the AI model’s output.
Put another way, weights are numerical parameters that define what’s most salient in a dataset for the given training task. They achieve their function by applying multiplication to inputs. Model training typically begins with weights that are randomly assigned, but as the process unfolds, the weights adjust as the model seeks to arrive at an output that more closely matches the target.
For example, an AI model for predicting housing prices that’s trained on historical real estate data for a target location could include weights for features such as the number of bedrooms and bathrooms, whether a property is detached or semi-detached, whether it has parking, a garage, and so on.
Ultimately, the weights the model attaches to each of these inputs reflect how much they influence the value of a property, based on the given dataset.
This article is updated regularly with new information.
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Tech
Dawn Myers is making it easier to style, detangle, and care for curly hair
Normally, Dawn Myers wears her hair up in a big old afro, and anyone with an afro can attest that wash days — the routine of washing and styling textured hair — are often tedious. They take a lot of detangling, product, styling, and, well, time.
“I was watching ‘Shark Tank,’ and there was another curly girl idea,” she recalled of a day around eight years ago, when a pitch for a hair product aired. She started thinking about all the hair tools on the market, like blow dryers and curling irons, “things that straighten and change the chemistry of our naturally curly hair,” she told TechCrunch, adding that it takes around an hour and 20 minutes to wash and style her own hair.
None of those tools help with that, and for Myers, it highlighted a gap that has always existed in the beauty hardware space — a lack of tooling for textured hair. It’s a space that’s complex, expensive, and just overlooked.
“If you think back to slavery, we were mandated to cover our hair. That’s where do-rags come from. You had to cover your hair. Why? Because our hair was seen as ugly and unkempt and unacceptable,” she said. Later came hot combs, chemical relaxers, and flat irons, all of which straighten textured hair. “It’s only been the past 15 years or so where women of color and Black women in particular and, quite frankly, white women as well have really felt comfortable exposing their naturally curly hair and really just embracing it.”
Soon after that episode aired, she whipped out a legal pad and sketched out a business idea, then went to Ace Hardware and CVS and put together a “Frankenstein-looking prototype.”
Her idea eventually became the company Richualist, which is known for its product Mint, a hair tool that helps detangle, condition, gel, and style in a single stroke using refillable product pods. It even has warming technology to gently heat the product before it’s applied.
“We get that styling time down to about seven to 10 minutes,” she said. “It’s a massive game changer for the customer really stressed out by wash day.” She said her product, which also comes in travel size, helps make hair a bit healthier, reducing shedding and breakage by up to 70% since people no longer need to tug endlessly on their strands as they wash and style.
She built it with the materials science company Dow, after an early prototype caught the company’s attention during a startup accelerator program. “It just so happens that Dow had identified this white space recently as well, and they were starting a textured hair care unit,” she said. “So they ended up collaborating with us and giving us a lot of engineering help and manufacturing guidance.”

Even though she eventually became one of the first 100 Black women to raise more than $1 million in venture funding, the early days were rough. “It’s really impossible to get hardware funded,” she continued. “It’s even more impossible to get it funded when we’re talking about such a niche problem.”
She recalled the early meetings with executives in the beauty industry. “There are no people who look like me in those R&D suites.” In fact, she said, when she described wash days, “these people didn’t know what a wash day was. They didn’t understand that there’s this whole process that their customers have to go through.” She would tell them how painful and arduous the process is. “And the powers that be, up until this point, did not know,” she continued. “Even the bonds in our hair are totally different than other technology types. We really do need bespoke technology.”
Myers sold her home and liquidated her 401(k) retirement account to fund the initial development of this product. “That was a crazy bet, but it paid off,” she said. “We were able to get about $1.4 million in the door to commercialize the product and just validate it.” Overall, it took about five years of development to get the product to “a place where it made sense to the customer,” she said, adding that her team also had to conduct their own research in the space since what they needed — like how much product the average person with textured hair uses — didn’t yet exist.
Then, in 2022, just as she was about to expand and go to market, she was diagnosed with stage three colorectal cancer. “We ended up closing our round while I was still going through treatment,” she recalled, saying the round took “forever” to close. She remembers sitting in the chemo chair at Johns Hopkins, on her laptop, trying to close deals. She applied to Shark Tank in 2023 and appeared on the show later that year, though the episode aired in 2024. “I was still wearing a binder around my abdomen [a compression wrap] under the dress I wore for my ‘Shark Tank’ experience,” she said.
She ended up nabbing a deal from investor Mark Cuban and serial entrepreneur Emma Grede, which helped her formally launch the product. Grede then helped it expand into Ulta’s online website earlier this year.
“We’re actually about to market ourselves as sold out,” she said, adding that the company is mapping out ways to expand further.
Her company was picked as one of TechCrunch’s Startup Battlefield 200 startups this year, earning a spot at TechCrunch Disrupt, the publication’s annual startup conference, which kicks off this Tuesday.
When asked how she first heard about Disrupt, she laughed. “I mean, who doesn’t know about Disrupt?” She said she’s bracing herself, as an introvert, for all the people she will meet and conversations she will have.
“But what I am most excited for is textured hair to be sitting on the stage with some of the most sophisticated tech in the space.”
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Tech
TechCrunch Mobility: A roadblock clears for self-driving trucks
Welcome back to TechCrunch Mobility, your hub for the future of transportation and now, more than ever, the role AI is playing in it. To get this in your inbox, sign up here for free — just click TechCrunch Mobility!
I’m back from a sojourn through New Hampshire’s White Mountains — a few days of respite before Disrupt 2026, TechCrunch’s annual tech conference in San Francisco. Now, after a few days immersed in fall colors, I am ready for the action. And there is gonna be a lot of it.
I want to see you all there, so here is a 30% discount on tickets to Disrupt with code mobility30. For more info on the show, scroll down.
Now, on to the news!
Self-driving truck companies Aurora Innovation and Kodiak AI received a federal exemption this week that removes a massive barrier to commercialization.
Under federal regulations, if a traditional big rig runs into trouble, the human driver must pull over, activate the hazard lights, and then physically place reflective warning triangles on the road within 10 minutes to alert other road users. But if a mechanical problem forces a self-driving truck to pull over, there’s no human driver to deploy those warning devices.
It was a big enough hurdle that Aurora took federal safety regulators to court over the requirement. After the court denied its request for an exemption, the company escalated the fight to the District of Columbia Court of Appeals. (Companies did have a temporary waiver as it awaited a decision.)
Now Aurora and other self-driving truck developers have been given the green light from the Federal Motor Carrier Safety Administration. The agency has granted a five-year exemption allowing companies to replace roadside warning devices, such as reflective warning triangles, with cab-mounted warning beacons. Check out Aurora’s first responders page to see how it works.

Daniel Goff, vice president of external affairs at Kodiak AI, said the exemption will help the industry “usher in an autonomous era of freight movement on U.S. roads, one that can save lives and improve the efficiency of goods delivery.”
Gerardo Interiano, Aurora’s head of government relations and public affairs, echoed that sentiment, saying the decision underscores the government’s recognition of the economic and community benefits of autonomous trucking. He described the high-visibility, cab-mounted warning beacons as a “critical, 21st-century solution that enhances roadside safety by immediately alerting other road users without ever needing to put a person in harm’s way.”
One question I’m left with: Could these cab-mounted warning beacons eventually become standard equipment across the entire trucking industry?
A little bird

It’s been a few months since Redwood Materials, the battery-recycling company started by Tesla co-founder JB Straubel, kicked off a restructuring to focus more on energy storage. The first stage of the restructuring involved laying off around 135 employees, or 10% of its workforce.
But a little bird recently told us that some more executives were on their way out the door. Sure enough, over the last few weeks, Redwood’s vice presidents of engineering, operations, treasury, and external affairs have all left the startup.
Got a tip for us? Email Kirsten Korosec at [email protected] or my Signal at kkorosec.07, or email Sean O’Kane at [email protected].
Deals!

Waymo has relied on capital from its parent company Alphabet and high-profile venture firms to fund its autonomous vehicle tech plans. This week, the company turned to debt financing for the first time for another bump. A $5 billion bump to be exact.
PIMCO, Blackstone, and Sixth Street were the lead lenders. But there were so many more, including Capital Group, Loomis Sayles, T. Rowe Price, Apollo, Blue Owl, Diameter Capital Partners, Franklin Templeton, Fidelity Management & Research Company, HPS Investment Partners, and Oaktree.
The debt financing comes as the company accelerates its commercial expansion within existing cities while pushing into new markets in the United States, Europe, and Japan.
Other deals that got my attention this week …
Bloom has raised $3.6 million to become the “Alibaba” of American manufacturing. The seed round was led by SNAK Venture Partners and included Flyover Capital, deep tech firm Mana Ventures, Detroit Venture Partners, Invest Detroit Ventures, and the Michigan Outdoor Innovation Fund.
Flai, a startup that developed AI software for dealerships, raised $27 million in a Series A funding round led by automation-focused firm Base10 Partners. The round included funding from dealers (Friedkin Group and Findlay Automotive), Toyota’s venture arm, Y Combinator, and First Round Capital.
Parallel Systems, a startup developing a rail vehicle capable of moving over several tons of freight as far as 500 miles without an operator, raised $100 million in a Series C round led by AVP, with participation from Hillspire, Agility Global, Cobalt Capital, Anthos Capital, Congruent Ventures, Riot Ventures, and Collaborative Fund.
Uber has agreed to buy catering company ezCater in an all-cash transaction valued at $2.3 billion.
Notable reads and other tidbits

Surveillance camera maker Flock cut its workforce by 18%, or around 270 employees, as the company faces ongoing and growing backlash to its license plate readers and people-tracking technology. FYI: Flock founder and CEO Garrett Langley will be at TechCrunch Disrupt 2026.
Lucid Motors built 2,954 electric vehicles in the third quarter of this year, a 54% drop from a year ago, as the company purposely limits production to better meet demand for its EVs.
Kodiak AI has a new 435-mile autonomous route between Dallas and Laredo, Texas, with carrier Charger USA. The self-driving trucks startup is hauling refrigerated and dry freight for consumer packaged goods and for food and beverage customers.
Tesla changed the name of its advanced driver assistance system in Europe after pushback from Germany’s transportation ministry. It’s now called “Tesla Assisted Driving” instead of “Full Self-Driving (Supervised).”
Uber and Chinese autonomous vehicle maker Pony.ai plan to launch a robotaxi service in London as part of an expanded partnership to bring driverless cars to Europe.
One more thing
Here’s a bit more info on TechCrunch Disrupt 2026!
I will kick off the conference on October 13 with Rivian CEO RJ Scaringe. Senior reporter Sean O’Kane has a fireside interview with Agility Robotics CTO Jonathan Hurst, as well as a panel featuring Also CEO Chris Yu, General Catalyst’s Yuri Sagalov, and Shan Shan, investment manager at Baillie Gifford.
I will also interview Shield AI CTO Nathan Michael; Waabi founder and CEO Raquel Urtasun; and Mikell Taylor, director of robotics strategy at GM about building AI systems when failure isn’t an option. And I will interview Foxglove CEO Adrian MacNeil and Bedrock Robotics CTO Kevin Peterson about taking physical AI from prototype to product.
Not enough? OK, here ya go: We will also have Max Hodak, co-founder of Neuralink and founder of Science Corp.; Ricursive Intelligence co-founders Dr. Anna Goldie and Dr. Azalia Mirhoseini; Hello Robot co-founder and CEO Aaron Edsinger and their robot Stretch 4; and Mark Wahlberg. Plus, hear from engineers and execs from Anthropic, Gamma, Hugging Face, OpenAI, Nvidia, and Replit, as well as investors from Google Ventures, Greylock, Eclipse, Index Ventures, NEA, and Upfront Ventures (to name a few.)
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Efferon wants to eradicate the devastating toll of pediatric sepsis
Sepsis, an acute inflammation triggered by infection, is a leading cause of childhood mortality, claiming roughly 3 million children under the age of five annually.
Efferon, a startup selected as one of TechCrunch Disrupt 2026’s Startup Battlefield 200, is on a mission to drastically lower that number.
The company has developed a medical device that it says lowers organ failure rates and significantly accelerates recovery in children.
When standard treatments like antibiotics cannot stop the immune system’s overreaction, a patient’s blood must be filtered to remove deadly toxins. That is where Efferon’s devices, of absorbers of dangerous cytokines and toxins, step in to make a critical difference.
Dima Romashin, Efferon’s co-founder and CEO, compares what happens in the body during sepsis to a fire, where an immune response overwhelms the body rapidly. “In a fire, there are two things: the flame itself and smoke that it produces,” he told TechCrunch.
In sepsis, endotoxins are the flames and cytokines are the smoke. Efferon, unlike other devices on the market, has developed a mechanism that can absorb both at once, according to Romashin.
Although Efferon makes absorbers for adults, Efferon NEO, its pediatric device developed specifically for young kids, is proving especially effective. Since children have a significantly lower circulating blood volume, they require medical devices engineered specifically for their physiology, according to Romashin.
In April, Efferon NEO received a CE mark, Europe’s equivalent to FDA approval, making it the first multimodal blood purification device specifically engineered for pediatric sepsis.
Efferon NEO is used in intensive care units across 30 countries, including European hospitals, Saudi Arabia, and Thailand. The company is now preparing to file for FDA approval and is on track to hit $2 million in annualized revenue by the end of 2026.
The startup’s technology was originally developed by scientists at Moscow State University, including co-founder Ivan Bessonov. Recognizing its potential, Romashin, a serial entrepreneur, stepped in earlier this year as CEO to help commercialize it.
Although Romashin admits that Efferon isn’t growing at the breakneck pace of today’s AI startups, true success for the company is measured by something else entirely: every child who gets to go home.
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